Microbial and Biochemical Pharmacy —— Midicinal Chemistry

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Home - Education - Ph.D. Supervisor - Microbial and Biochemical Pharmacy —— Midicinal Chemistry

SUN Chenghang

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time:2021-12-14

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Name:SUN Chenghang

Department:Microbial Chemistry

Tel: (8610) 63165272

Email:sunchenghang@imb.pumc.edu.cn

Education & Research Experience:

2007/07 – Now,Professor, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences

2002/03 – 2003/12,Postdoctoral training, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, USA

2000/01 – 2002/01,Oversea Researcher, Kitasato Institute, Japan;

1996/09 – 1999/12,Ph.D Student. in Microbial and Biochemical Pharmacy, Peking Union Medical College

Research Field:

Prospecting of pharmaceutical actinobacteria from extreme environments and discovery of novel antibiotics

Research Interests:

1. Isolation and structural identification of new antibiotics by modern chromatography and spectroscopy;

2. Discovery and identification of new species of pharmaceutical actinobacteria by polyphasic taxonomy from special environments such as Mangrove, Desert, Soda lakes, Karst Cave, etc;

3. Directly bioprospecting new antibiotic producing strains and highly efficiently discovery of new antibiotics by modern analytic methods such as GNPS etc.

Selected Publications:

1. Wang Ting, Li Feina, Lu Qinpei, Habden Xugela, Razumova Elizaveta A., Osterman Ilya A., Sergiev Petr V., Dontsova Olga A., You Xuefu and Sun Chenghang*: Studies on diversity, novelty, antimicrobial activity and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected in Taklamakan desert. Journal of Pharmaceutical Analysis. 2021,11(2): 241-245. https://doi.org/10.1016/j.jpha.2020.06.004

2. Wu, Gang, Wang, Ting, Jiang, Zhongke, Liu, Shaowei, Sun, Chenghang*: Asymmetric Total Synthesis of Hetiamacins A–F. ACS Omega 2021, 6, 8239–8245 https://doi.org/10.1021/acsomega.0c06267

3. Shao-wei Liu, Ting Wang, Qin-pei Lu1, Fei-na Li, Gang Wu, Zhong-ke Jiang, Xugela Habden, Lin Liu, Xiao-lin Zhang, Dmitrii A. Lukianov, Ilya A. Osterman, Petr V. Sergiev, Olga A. Dontsova and Cheng-hang Sun* : Bioprospecting of Soil-Derived Actinobacteria along the Alar-Hotan Desert Highway in the Taklamakan Desert. Frontiers in microbiology 2021, Volume12 Article 604999,dio:10.3389/fmicb.2021.604999

4. Mohsin Tassawar Cheema, Jing-Jing Ye, Fei-Na Li, Qin-Pei Lu, Muhammad Abbas, Imran Sajid, Da-Lin Huang, Shao-Wei Liu* and Cheng-Hang Sun*: Auraticoccus cholistanensis sp. nov., an actinomycete isolated from soil of the Cholistan Desert, and emended description of the genus Auraticoccus.International Journal of Systematic and Evolutionary Microbiology 2020;70(5): 3179-3185. https://doi.org/10.1099/ijsem.0.004152

5. Zhong-Ke Jiang, Xin-Xin Hu , Lan-Lin Xiao,Yi-Ru Ren , Anna N. Shakhtina , Dmitrii A. Lukianov , Ilya A. Osterma, Petr V.Sergiev , Olga A. Dontsova, Hao Wang, Gang Wu, Xue-Fu You, and Cheng-Hang Sun*: Beilunmycin, a new virginiamycins antibiotic from mangrove-derived Streptomycessp. 2BBP-J2 and the antibacterial activity by inhibiting translation. Journal of Asian Natural Products Research. 2020, https://doi.org/10.1080/10286020.2020.1810669

Awards and Honors:

1. “Discovery of Minor and Novel Compounds by application of theory of isolation and purification”is awarded as the third prize of S&T development in 1997 approved by Ministry of Public Health, China

2. “R&D of Biopesticide,Duokangling” is awarded as the first prize of S&T development in 1999 approved by Zhejiang Province.

3. Excellent teacher is honored for three years in a row from 2017-2019 by Institute of Medicinal Biotechnology, Peking Union Medical Colleges.

Academic Appointments:

Editorial Board of Chinese Journal of Antibiotics, Editorial Board of Chinese Medicinal Biotechnology