Microbial and Biochemical Pharmacy —— Midicinal Chemistry

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Home - Education - Ph.D. Supervisor - Microbial and Biochemical Pharmacy —— Midicinal Chemistry

SUN Chenghang

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NameSUN Chenghang

DepartmentMicrobial Chemistry

Tel: (8610) 63165272

Email:sunchenghang@imb.pumc.edu.cn

Education & Research Experience

2007/07 – NowProfessor, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences

2002/03 2003/12,Postdoctoral training, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, USA

2000/01 2002/01,Oversea Researcher, Kitasato Institute, Japan;

1996/09 – 1999/12Ph.D Student. in Microbial and Biochemical Pharmacy, Peking Union Medical College

Research Field

Prospecting of pharmaceutical actinobacteria from extreme environments and discovery of novel antibiotics

Research Interests

1. Isolation and structural identification of new antibiotics by modern chromatography and spectroscopy;

2. Discovery and identification of new species of pharmaceutical actinobacteria by polyphasic taxonomy from special environments such as Mangrove, Desert, Soda lakes, Karst Cave, etc;

3. Directly bioprospecting new antibiotic producing strains and highly efficiently discovery of new antibiotics by modern analytic methods such as GNPS etc.

Selected Publications

1. Wang Ting, Li Feina, Lu Qinpei, Habden Xugela, Razumova Elizaveta A., Osterman Ilya A., Sergiev Petr V., Dontsova Olga A., You Xuefu and Sun Chenghang*: Studies on diversity, novelty, antimicrobial activity and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected in Taklamakan desert. Journal of Pharmaceutical Analysis. 2021112: 241-245. https://doi.org/10.1016/j.jpha.2020.06.004

2. Wu, Gang, Wang, Ting, Jiang, Zhongke, Liu, Shaowei, Sun, Chenghang*: Asymmetric Total Synthesis of Hetiamacins A–F. ACS Omega 2021, 6, 8239–8245 https://doi.org/10.1021/acsomega.0c06267

3. Shao-wei Liu, Ting Wang, Qin-pei Lu1, Fei-na Li, Gang Wu, Zhong-ke Jiang, Xugela Habden, Lin Liu, Xiao-lin Zhang, Dmitrii A. Lukianov, Ilya A. Osterman, Petr V. Sergiev, Olga A. Dontsova and Cheng-hang Sun* : Bioprospecting of Soil-Derived Actinobacteria along the Alar-Hotan Desert Highway in the Taklamakan Desert. Frontiers in microbiology 2021, Volume12 Article 604999dio:10.3389/fmicb.2021.604999

4. Mohsin Tassawar Cheema, Jing-Jing Ye, Fei-Na Li, Qin-Pei Lu, Muhammad Abbas, Imran Sajid, Da-Lin Huang, Shao-Wei Liu* and Cheng-Hang Sun*: Auraticoccus cholistanensis sp. nov., an actinomycete isolated from soil of the Cholistan Desert, and emended description of the genus Auraticoccus.International Journal of Systematic and Evolutionary Microbiology 2020;70(5): 3179-3185. https://doi.org/10.1099/ijsem.0.004152

5. Zhong-Ke Jiang, Xin-Xin Hu , Lan-Lin Xiao,Yi-Ru Ren , Anna N. Shakhtina , Dmitrii A. Lukianov , Ilya A. Osterma, Petr V.Sergiev , Olga A. Dontsova, Hao Wang, Gang Wu, Xue-Fu You, and Cheng-Hang Sun*: Beilunmycin, a new virginiamycins antibiotic from mangrove-derived Streptomycessp. 2BBP-J2 and the antibacterial activity by inhibiting translation. Journal of Asian Natural Products Research. 2020, https://doi.org/10.1080/10286020.2020.1810669

Awards and Honors:

1. “Discovery of Minor and Novel Compounds by application of theory of isolation and purification”is awarded as the third prize of S&T development in 1997 approved by Ministry of Public Health, China

2. “R&D of BiopesticideDuokangling” is awarded as the first prize of S&T development in 1999 approved by Zhejiang Province.

3. Excellent teacher is honored for three years in a row from 2017-2019 by Institute of Medicinal Biotechnology, Peking Union Medical Colleges.

Academic Appointments

Editorial Board of Chinese Journal of Antibiotics, Editorial Board of Chinese Medicinal Biotechnology