中国医学科学院医药生物技术研究所

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2014年药生所发表SCI论文统计表(影响因子>3)
来源:科教处 时间:2015-07-01 浏览次数:3422

序号

论文名称

影响因子

作者(英文名)

杂志名称

1

A Poly-N-acetylglucosamine-Shiga toxin broad-spectrum conjugate vaccine for Shiga toxin-producing Escherichia coli

6.875

Lu X, Skurnik D, Pozzi C, Roux D, Cywes-Bentley C, Ritchie JM, Munera D, Gening ML, Tsvetkov YE, Nifantiev NE, Waldor MK, Pier GB

mBio

2

A tumor-targeting dextran-apoprotein conjugate integrated with enediyne chromophore shows highly potent antitumor efficacy.

5.231

Bin Li, Xiu-jun Liu, Liang Li, Sheng-hua Zhang, Yi Li, Dian-dong Li and Yong-su Zhen

Polymer Chemistry

3

Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT

5.119

Yanni Xu,1,§ Qi Liu,1,§ Yang Xu,1 Chang Liu,1 Xiao Wang, 1 Xiaobo He,1 Ningyu Zhu, 1 Jikai Liu,1 Yexiang Wu,1 Yongzhen Li,1 Ni Li,1 Tingting Feng,1 Fangfang Lai,2 Murui Zhang,3 Bin Hong,1,* Jian-Dong Jiang,1,2* Shuyi Si.1,*

journal of lipid research

4

Identification of a novel partial agonist of liver X receptor a (LXRa) via screening

4.650

Ni Li a,b, Xiao Wanga, Jing Zhang a, Chang Liu a, Yongzhen Li a, Tingting Feng a, Yanni Xu a,*,

Biochemical Pharmacology

5

In Vivo Antibacterial Activity of MRX-I, a New Oxazolidinone

4.451

Cong-Ran Li, Qian-Qian Zhai, Xiu-Kun Wang, Xin-Xin Hu, Guo-Qing Li, Wei-Xin Zhang, Jing Pang, Xi Lu, Hong Yuan, Mikhail Fedorovich Gordeev, Le-Tian Chen, Xin-Yi Yang, Xue-Fu You

Antimicrobial Agents and Chemotherapy

6

The antituberculosis antibiotic capreomycin inhibits protein synthesis by disrupting interaction between ribosomal proteins L12 and L10.

4.451

Lin Y1, Li Y, Zhu N, Han Y, Jiang W, Wang Y, Si S, Jiang J.

Antimicrob Agents Chemother.

7

Characterization of an Ebosin derivative produced by heterologous gene replacement in Streptomyces sp. 139

4.250

Zhang Y, Shan Junjie, Bao Yonggang, Bai Liping, Jiang Rong, Guo Lianhong, Yao Chen, Zhang Ren and Li Yuan

Microbial Cell Factories

8

Src mediates extracellular signal-regulated kinase 1/2 activation and autophagic cell death induced by cardiac glycosides in human non-small cell lung cancer cell lines.

4.200

Wang Y, Zhan Y, Xu R, Shao R, Jiang J, Wang Z

Molecular Carcinogenesis

9

NRPS substrate promiscuity leads to more potent antitubercular sansanmycin analogues

3.947

Xie, Y.; Cai, Q.; Ren, H.; Wang, L.; Xu, H.; Hong, B.; Wu, L.; Chen, R.

journal of natural produtcts

10

6-Deoxy-13-hydroxy-8,11-dione-dihydrogranaticin B, an intermediate in granaticin biosynthesis, from Streptomyces sp. CPCC 200532

3.900

Bingya Jiang, Shufen Li, Wei Zhao, Ting Li, Lijie Zuo, Yanni Nan, Linzhuan Wu, Hongyu Liu, Liyan Yu, Guangzhi Shan, and Limin Zuo

J Nat Prod

 

An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer

3.730

Xiao-Fang Guo., Xiao-Fei Zhu., Wan-Cai Yang, Sheng-Hua Zhan5, Yong-Su Zhen*

PLoS One

11

Tuftsin-based, EGFR-targeting fusion protein and its enediyne-energized analog show high antitumor efficacy associated with CD47 down-regulation.

3.637

Wen‑Juan Liu · Xiu‑Jun Liu · Liang Li · Yi Li ·Shenghua Zhang Yongsu Zhen

Cancer Immunol Immunother

12

A multifunctional drug combination shows highly potent therapeutic efficacy against human cancer xenografts in athymic mice

3.534

Xiu-Jun Liu, Yan-Bo Zheng, Yi Li, Shu-Ying Wu, Yong-Su Zhen

PLoS ONE

13

Novel N-substituted sophoridinol derivatives as anticancer agents.

3.432

Chong-Wen Bi,Cai-Xia Zhang,Ying-Hong Li,Sheng Tang,Hong-Bin Deng,Wu-Li Zhao,Zhen Wang,Rong-Guang Shao, Dan-Qing Song

European Journal of Medicinal Chemistry

14

Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2ep53 interaction

3.432

Guang-hui Zheng, Jia-jia Shen, Yue-chen Zhan, Hong Yi, Si-tu Xue, Zhen Wang,Xing-yue Ji*, Zhuo-rong Li*

European Journal of Medicinal Chemistry

15

Design, synthesis and antiproliferative activity of a novel class of indole-2-carboxylate derivatives

3.432

Xing-yue Ji 1, Si-tu Xue 1, Yue-chen Zhan, Jia-jia Shen, Lin-tao Wu, Jie Jin, Zhen Wang

European Journal of Medicinal Chemistry

16

Synthesis, antimycobacterial and antibacterial evaluation of l-[(1R, 2S)-2-fluorocyclopropyl]fluoroquinolone derivatives containing an oxime functional moiety

3.432

Hongmin Liu,  Ju Huang,  Jiayang Wang,  Minghua Wang,  Mingliang Liu,  Bin Wang,  Huiyuan Guo,  Yu Lu

European Journal of Medicinal Chemistry

17

Phosphorylation of myofibrillogenesis regulator-1 activates the MAPK signaling pathway and induces proliferation and migration in human breast cancer MCF7 cells

3.341

Yuyan Gong, Hongwei He, Hong Liu, Caixia Zhang, Wuli Zhao, Rong-guang Shao

FEBS LETTERS

18

Small-sized polymeric micelles incorporating docetaxel suppress distant metastases in the clinically-relevant 4T1 mouse breast cancer model

3.330

Yunfei LiMingji JinWei HuangFeifei YangShenghuaZhangGuimin Xiaand Zhonggao Gao

BMC cancer

19

Optimization of Rutaecarpine as ABCA1 Up-Regulator for Treating Atherosclerosis.

3.320

Li Y, Feng T, Liu P, Liu C, Wang X, Li D, Li N, Chen M, Xu Y, Si S.

ACS Med Chem Lett.

20

Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin.

3.287

Xing-qi Li, Zhi-gang Ouyang, Sheng-hua Zhang, Hong Liu, Yue Shang, Yi Li and Yong-su Zhen

Cancer Biology & Therapy

21

Cardiotoxicity evaluation of anthracyclines

3.174

Ying Han, Jing-pu Zhang*, Jian-qin Qian and Chang-qin Hu

J Appl Toxicol

22

Preparation and evaluation of a CD13/APN-targeting and hydrolase-resistant conjugate that comprises pingyangmycin and NGR motif-integrated apoprotein.

3.130

BIN LI, YAN-BO ZHENG, DIAN-DONG LI, YONG-SU ZHEN

JOURNAL OF PHARMACEUTICAL SCIENCES

23

Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction.

3.117

Xing-Qi Li ?Zhi-Gang Ouyang ?Sheng-Hua Zhang ong

J Neurooncol

24

Synthesis and Biological Evaluation of Sophoridinol Derivatives as a Novel Family of Potential Anticancer Agents

3.073

Chongwen Bi, Caixia Zhang, Yinghong Li, Sheng Tang, Shenggang Wang, Rongguang Shao, Haigen Fu, Feng Su,Danqing Song

ACS Medicinal Chemistry Letters